Abbreviation or jargon used	Abbreviation expanded	Significance
ADME	Absorption, distribution, metabolism, elimination	Progress of a medicine in an organism
AMM	Marketing authorizations
BPL	Good laboratory practises	All the international norms of methodology, in laboratory, clinical or manufacturing practise,
BPC	Good clinical practises
BPF	Good manufacturing practises
CdB	Croix de Berny	Aventis unit grouping a part of the clinical development
CPR	Romainville production centre	Production factory of Aventis at 111 rte de Noisy
CRVA	Vitry / Alforville research centre
CRO	Contract research organisation	Unit of sub-contracting of clinical development
DMPK	Distribution, metabolism & pharmacokinetic	Progress of a medicine in the organism
EDC	Early development candidate	Product in pre-clinic survey
EMEA	European Medicine Agency
FDA	Food & drug administration	American agency which delivers the AMMs
GRAMS	Aventis jargon designating the services of the regulatory bodies
HERG	Human ether a gogo related gene	In vitro test permitting to foresee a deleterious effect of a molecule on the electrocardiogram (QT).
Hit	Chemical head of series capable of supplying some « leads »
HTS	High throuput screening	High speed molecular “sifting”
lead		Potential EDC but improvable
PR	Product realisation	Designate the services of (and bound to them) clinical studies IIb and III
R&D	Research and development
NMR	Nuclear magnetic resonance	Methodology capable of determining the atomic composition of a molecule
Rmv	Romainville
SNC	Central nervous system